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Also, wear protective clothing and hats, and apply creams, lotions, or moisturizers often. The manufacturer of the medicine is Shahnaz Husain, India. Deputy Medical Superintendent & I/C, Male Infertility Unit, Department of Prasuti Tantra, Institute of Medical Sciences, Sir Sunderlal Hospital, Banaras Hindu University, Varanasi, India, Indian Journal of Clinical Practice (2003): (14), 2, 29-31. Both drugs exhibit anticholinergic effects that may be additive. The metabolism of Mephenytoin can be decreased when combined with Haloperidol. Patients with renal impairment: In patients with severe renal impairment (creatinine clearance less than 30 mL/min), the usual recommended dose is 250 mg once daily.