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The metabolism of Pipotiazine can be decreased when combined with Fluvoxamine. Roaccutane should not be used for the treatment of prepubertal acne and is not recommended in children less than 12 years of age due to a lack of data on efficacy and safety. The metabolism of Morphine can be increased when combined with Phenytoin. Within each category the following adverse reactions are listed in order of decreasing severity. Syrup – Depakene by Abbott Laboratories. Very rarely men complain of side effects after taking Forzest.